A Liverpool-born midfielder, Darren had brief youth associations with Everton and Blackburn Rovers before joining the development setup of Liverpool. Coming through the ranks at Anfield, Potter was a talented prospect, representing Ireland at the 2003 FIFA World Youth Championship. He made his senior Liverpool debut on 10th August 2004 in a UEFA Champions League qualifier against Austrian club Grazer AK.
After just one further Liverpool appearance, Potter spent the second half of 2005-06 on loan at Southampton, joining the Saints in January 2006. He would make 12 appearances whilst at St. Mary's.
The following season, 2006-07, Darren spent the first half of the campaign on loan at Championship Wolverhampton Wanderers before completing a £250,000 permanent transfer to Molineux in January 2007.
A total of 96 appearances for Wolves preceded a loan spell at Sheffield Wednesday, with whom he spent the second half of the 2008-09 season, playing 17 games and scoring twice. Potter would join the Owls permanently in summer 2009, and would play 49 matches during the 2009-10 season in which Wednesday were relegated to League One. Whilst in League One, Darren would add 40 games and 4 goals to his Hillsborough total, the final tally reading 9 goals in 106 matches.
Potter's Molineux tenure also led to him making his senior international debut, playing in Republic of Ireland's friendly with Ecuador on 23rd May 2007. This would be the first of 5 international caps awarded to Darren between 2007 and 2008.
He joined Milton Keynes Dons in 2011, kickstarting a successful period in his personal career. Over 6 seasons, Potter represented the Dons 267 times and scored 12 goals in all competitions. His contribution helped them secure automatic promotion to the Championship at the end of the 2014-15 season.
On an individual basis, Potter's time at Stadium:MK was fruitful, earning the Player of the Year and Players' Player of the Year awards for the 2011-12 season. He was also named in the PFA League One Team of the Year for 2011-12.
He made the transfer to League One Rotherham United on 14th June 2017, signing a 2-year contract. Unfortunately, a serious Achilles injury sustained against Bristol Rovers on 2nd December 2017 kept him out of action for almost three-quarters of his contract, making just one further appearance for the Millers (5th May 2019 vs. Middlesbrough).
He was released in the summer of 2019 and signed a 1-year deal with Tranmere on 28th June 2019, joining Micky Mellon's side in their return to League One.
Interesting Fact: Darren once played in the UEFA Champions League. He came on as an 86th-minute substitute in Liverpool's 3-1 Round of 16 first-leg victory over Bayer Leverkusen on 22nd February 2005.